Resistance to change starts all the way up to the level of the individual cell inside your body. It starts with what it needs are, and then the way it interacts with the brain and what imagery the brain formulates and the solution it releases. Now, the imagery the brain formulates is based on previous experiences. ….It begins with the perspective of the cell; the cell know where it is, where it’s going and what proteins it’s making, when it’s about to divide, when it’s programmed to stop dividing and knows what it needs are. The cell, in some sense, is the smallest unit of consciousness of the body. The time the cell has a need, it yells up to the brain: I haven’t got my fix today. And it starts sending impressions to the brain. The brain then starts to formulate imaginary. The brain starts to think of a reason why we have a certain need. It tries to figure out why we’re depressed, confused or hungry. The brain tries to offer a solution by going through our past situations and experiences and creates orders that offer the appropriate action to the solution.
The orders come from the neuronet in our brain. The neuronet is based on the experiences and information locked in there. We use a certain box of solutions to our life that cause chemistry to take place. In order for us to change the chemistry, thus the solution, we would literally have to change the neuronet. Which means we have to change our know-how, attitude and the way we interact with our environment. Every time we keep being the same person and keep experiencing the same attitude, all we’re doing is reinforcing ourselves as our identity. This is part of human nature; we try to maintain expressing old patterns for as long as possible, right until the moment of crisis.
So how does the brain formulate a solution? There is a part of the brain, called the hypothalamus, that is like a mini factory and it is a place that assembles certain chemicals that match certain emotions we experience. Those particular chemicals are called peptides. Simply said peptides match the emotional state we experience on a daily basis. So there are peptides for happiness anger, sadness, lust and about twenty more. There is a chemical that matches every emotional state we experience. And the moment we experience that emotional state in our body or in our brain, that hypothalamus will immediately assemble the peptide and releases it into the bloodstream. The moment they enter the bloodstream, the peptides will find their way to different centers or different parts of the body. Now, every single cell in the body has these receptors on the outside which are sensitive to these peptides. One cell can have thousands of receptors on its surface, with which it is kind of opening up to the outside world. When a peptide docks on a cell it is like a key going into a lock, sits on the receptor surface and attaches to it and send a signal into the cell.
Peptides come off and come back again. While they’re there, they’ll change the cell. A receptor with a peptide sitting in it sets off a cascade of biochemical events, some of which change the nucleus of the cell. With each cell being alive and having a sort of consciousness and it knows so by previous experiences.
These peptides are such strong chemicals that are so addictive that it becomes really hard to bring in something new into your life. (comfort zone) Situations are known which show that it is so hard not to meet the addiction of certain peptides that one will collapse physically before trying a different solution. This is also for example what stress does to our body, we becom e so addictive to the stress that we can’t quit our job even though it doesn’t serve us or we can’t leave a relationship because it doesn’t serve us. We can be stuck in the situation. We can’t make choices because the stimulus and responses produces the chemistry that clouds those choices.
What we do is to create situations that fulfill the biochemical craving of the cells of our body, by creating situations that meet our chemical needs. As in all addiction we keep begin stuck in old patterns, we want to be within our comfort zone for as long as possible. Only when the crisis is high enough, people will try the unfamiliar. Once taken the first step into the unfamiliar, that moment of insight carries a new message. And if experienced, a new concept emerges. The information processed will leave its footprints in the brain and a perception of the world can change.

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Great thoughts Stefan… does this mean we can cure shopping or over-eating by either medicine (if we could reprogram the synapses - bottom-up) or by mental-programming (reframing by NLP for example?! - top down) Interesting.
I wonder if your thoughts require also to adopt Dawkins vision of the Selfisch Gene?!
“Instead of thinking about organisms using genes to reproduce themselves, as we had since Mendel’s work was rediscovered, we turn it around and imagine that “our” genes build and maintain us in order to make more genes.”
http://en.wikipedia.org/wiki/The_Selfish_Gene
It is fascinating that neuro-scientists report similar results… they cannot see what you think but do measure how you respond to certain events (negative, positive etc). They claim that most advertisers or markerteers have really no clue what they are doing =)
A crazy example of this I found this weekend (sorry a little bit of topic)…
[video]http://www.youtube.com/v/Sw871vN2c18&rel=1[/video]
Marketeers think in awareness and in this case thought my name is extreme so I can do an extreme viral-movie. Neatly done, meybe even a bit funny, but the big connotation is airplane-crash. So how are your genes responding to this and how is X-treme-travel now programmed mentally in your evoked set??? Is this an example of superficial-marketing appealing to the wrong memes?
I’m not much of a biochemist, and I’m not sure what dynamics precisely exist between genes and cells. My guess is that eating disorders or shopping addictions would be cured by something like NLP rather than bottom-up reprogramming of the synapses
because the brain determines the solution, not the cells. The cells have a need and then yell to the brain, which in its turn formulates the imagery to the solution. A shopping disorder in that sense would start with a feeling of unhappiness or such, to which the brain formulates the imagery of shopping. Apparently the action of shopping releases the appropriate peptides, which satisfy the cell’s needs.
Our experiences color what we know. So there is no complete objective appraisal of anything. Our appraisal of everything has to do with our previous experiences and emotions. Everything has an emotional weighting to it. When a specific unsatisfied urge was previously solved by the action of shopping, it’s hard to formulate another solution without stepping out of your comfort zone. So, yes, the metal picture has to be changed in order to change the offered solution of shopping.
To the example of the plane crash X-treme travel commercial…. Personally, and in retrospect, I liked the commercial. While having no idea what was coming and seeing the plane go down, I felt a sense of anxiety. Once the clue was presented I laughed out loud, probably because initially my senses where wide open because of the initial emotion. Now, the second time I saw the example, I showed it to a colleague and was smiling from the start, in anticipation of what was to come, in anticipation of the emotion I am addicted to. But I don’t think my mental picture and anticipation of seeing a plane crash have changed…. Yet
But…one of the things about receptors is that they change in their sensitivity. If a given receptor for a certain juice is bombarded for a long time with a high intensity, it will literally shrink up, there will be less of them, or it will be hooked up in such a way that it is desensitized. So the same amount of internal juice will provide a much smaller response.
(interesting twist of the same material we saw
down the rabit hole)
i have the same question as arjan, only differently framed. i believe we are very much biological animals, much of our behavior is instinctive and fits the environment of 100.000 ears ago quite well. this is explained by your description of the function of the hypothalamus, i think. this can either become the best excuse for not changing or lead to more revolutionary ways of changing. (instead of evolutionary.) what do you think? will applied NLP take over the world (if it works, i think it might/will)? or will we see a general acceptance? will we start to feel victimized by our evolutionary ancestry?
I think everything can be framed or reframed. To you remark whether NLP will take over the world, I think in regard to its reframing abilities, yes. Maybe a better word for this is PR, as Freud’s nephew Edward Bernays used it for manipulating the public’s opinion in lot of matters. He got woman smoking under the flag of independency in the early 20’s by bombarding the unconsciousness with imagery and messaging over mass media, framing or reframing all kinds of matter. You could say he founded a new wave of capitalism, changing it from a system that fulfilled needs, to a system the created needs. He used mass media for altering mental pictures.